Background: Septate uterus is a common Mullerian ducts anomaly. The aim of our pilot study was the evaluation
of diode laser hysteroscopic metroplasty efficacy to increase endometrial volume in women with septate uterus.
Results: We prospectively enrolled 10 consecutive patients with septate uterus undergoing office hysteroscopic
metroplasty with diode laser between February and November 2019. Endometrial volume was evaluated before
and 3 months after surgery using 3D transvaginal ultrasound. The surgical procedure was uncomplicated in all
patients, the endometrial volume increased at 3 months follow-up (the median increase was 1.9 cm3 (range 1.7–
2.1), and there was a complete removal of septum with no intrauterine synechiae at follow-up hysteroscopy.
Conclusions: Office hysteroscopic metroplasty with diode laser is a safe procedure and has preliminary showed to
increase endometrial volume. The increase in endometrial volume by 3D-TV US could be used as a prognostic
factor for the reproductive outcomes.
Keywords: Septate uterus, Metroplasty, Diode laser, Hysteroscopy, 3D ultrasound